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Protropin is a synthetic (man-made) version of human growth hormone (HGH), a naturally occurring substance thats produced by the pituitary gland which primarily stimulates growth in children. Protropin is approved for use in children who have certain conditions which restrict normal growth and development, such as a growth hormone deficiency due to reduced natural HGH production, kidney disease, Prader-Willi Syndrome (PWS), and Turner’s syndrome. Protropin was most often used in adults to treat both growth failure and weight loss caused by acquired immunodeficiency syndrome (AIDS).
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Protropin is a white powder intended for intramuscular or subcutaneous administration by injection after reconstitution with Bacteriostatic Water. With growth hormone therapy in adults, increases in lean body mass and physical performance, and decreases in body fat and waist circumference are seen.
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Protropin (somatrem for injection), is a polypeptide hormone produced by recombinant DNA technology. Protropin has 192 amino acid residues and a molecular weight of about 22,000 daltons. The product contains the identical sequence of 191 amino acids constituting pituitary-derived human growth hormone plus an additional amino acid, methionine, on the N-terminus of the molecule. Protropin is synthesized in a special laboratory strain of E. coli bacteria which has been modified by the addition of the gene for human growth hormone production.